Ursula Grohmann Selected Research

Type 1 Diabetes Mellitus (Autoimmune Diabetes)

1/2020	Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine.
11/2018	Immune Checkpoint Molecules, Personalized Immunotherapy, and Autoimmune Diabetes.
1/2018	Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes.
1/2018	Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes.
1/2017	The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes.
10/2015	Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes.
11/2009	IDO mediates TLR9-driven protection from experimental autoimmune diabetes.
10/2009	Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.

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Ursula Grohmann Research Topics

Disease

15	Neoplasms (Cancer) 10/2022 - 06/2002
13	Inflammation (Inflammations) 10/2021 - 05/2007
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 10/2009
5	Multiple Sclerosis 11/2020 - 08/2010
5	Starvation 01/2017 - 06/2006
4	Autoimmune Diseases (Autoimmune Disease) 11/2020 - 07/2003
3	Neuroinflammatory Diseases 01/2020 - 08/2010
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020 - 08/2010
3	Infections 06/2017 - 01/2010
3	Hypersensitivity (Allergy) 01/2013 - 05/2007
2	Weight Gain 01/2021 - 11/2018
2	Obesity 01/2021 - 11/2018
2	Arthritis (Polyarthritis) 01/2020 - 10/2016
2	Shock 02/2015 - 05/2006
2	Prediabetic State (Prediabetes) 10/2004 - 07/2003
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2021
1	Nephritis 01/2021
1	Metabolic Diseases (Metabolic Disease) 01/2021
1	Erythema 01/2021
1	Proteinuria 01/2021
1	Insulin Resistance 01/2021
1	Glomerulonephritis 01/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021
1	Hypertrophy 01/2021
1	Thyroiditis 12/2020
1	Glioma (Gliomas) 10/2020
1	Glioblastoma (Glioblastoma Multiforme) 10/2020
1	Brain Neoplasms (Brain Tumor) 10/2020
1	Colitis 01/2020
1	Rheumatoid Arthritis 01/2020
1	Central Nervous System Diseases (CNS Diseases) 01/2018
1	Vomiting 08/2017
1	Bulimia (Binge Eating) 08/2017
1	Weight Loss (Weight Reduction) 08/2017
1	Multiple Myeloma 01/2017
1	Hemophilia A (Haemophilia) 10/2015
1	Necrosis 10/2014
1	Virus Diseases (Viral Diseases) 01/2013

Drug/Important Bio-Agent (IBA)

14	Tryptophan (L-Tryptophan)FDA Link 10/2022 - 07/2003
14	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 04/2022 - 10/2007
9	CytokinesIBA 01/2021 - 10/2004
8	EnzymesIBA 01/2021 - 07/2007
7	Pharmaceutical PreparationsIBA 10/2021 - 05/2007
4	Interleukin-6 (Interleukin 6)IBA 01/2021 - 05/2006
4	InterferonsIBA 08/2012 - 07/2003
3	KynurenineIBA 01/2021 - 01/2008
3	Amino Acids FDA Link 01/2020 - 01/2017
3	Interleukin-12 (IL 12)IBA 01/2013 - 06/2002
2	Immune Checkpoint InhibitorsIBA 01/2021 - 10/2020
2	Arginine (L-Arginine)FDA Link 01/2020 - 04/2019
2	LigandsIBA 11/2019 - 05/2007
2	Proteins (Proteins, Gene)FDA Link 04/2019 - 06/2002
2	AutoantigensIBA 01/2018 - 01/2017
2	Biological ProductsIBA 01/2018 - 08/2008
2	AntigensIBA 10/2016 - 10/2015
2	metabotropic glutamate receptor 4IBA 03/2016 - 08/2010
2	EndotoxinsIBA 02/2015 - 07/2014
2	Interleukin-23 (Interleukin 23)IBA 01/2013 - 05/2006
2	Peptides (Polypeptides)IBA 11/2004 - 06/2002
1	Essential Amino AcidsIBA 10/2022
1	vedolizumabIBA 10/2021
1	Interleukin-17 (Interleukin 17)IBA 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	NitrogenIBA 01/2021
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	tocilizumab (atlizumab)FDA Link 01/2021
1	Immunoglobulin A (IgA)IBA 12/2020
1	PolyaminesIBA 11/2020
1	SpermidineIBA 11/2020
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 10/2020
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 10/2020
1	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2020
1	Neuroprotective AgentsIBA 01/2020
1	AntioxidantsIBA 01/2020
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2020
1	Serotonin (5 Hydroxytryptamine)IBA 01/2020
1	nasIBA 01/2020
1	N-acetylserotoninIBA 01/2020
1	Fingolimod Hydrochloride (FTY720)FDA Link 11/2019
1	Sphingosine-1-Phosphate ReceptorsIBA 11/2019
1	ArginaseIBA 04/2019
1	AutoantibodiesIBA 04/2019
1	SolutionsIBA 11/2018
1	Immune Checkpoint ProteinsIBA 11/2018
1	DiureticsIBA 08/2017
1	LaxativesIBA 08/2017
1	Bortezomib (Velcade)FDA Link 01/2017
1	Proteasome InhibitorsIBA 01/2017
1	Tyrosine (L-Tyrosine)FDA Link 01/2017
1	methylated bovine serum albumin (MBSA)IBA 10/2016
1	5- methyl- N- (4- methylpyrimidin- 2- yl)- 4- (1H- pyrazol- 4- yl)thiazol- 2- amineIBA 03/2016
1	AntibodiesIBA 10/2015
1	Blood Coagulation Factors (Coagulation Factor)IBA 10/2015
1	Factor VIII (Coagulation Factor VIII)IBA 10/2015
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 02/2015
1	Interleukin-27 (Interleukin 27)IBA 01/2013

Therapy/Procedure

8	Immunotherapy 01/2021 - 07/2003
6	Therapeutics 12/2020 - 08/2008
1	Injections 01/2020